Under the bright lights of an operating theatre in Delhi, a woman lies motionless as surgeons prepare to remove her gallbladder. She sleeps under general anaesthesia, her body paralysed and her mind unconscious. Yet a gentle stream of flute music plays through headphones resting over her ears. Even as anaesthetic drugs silence much of her brain, the auditory pathways remain partially active. When she wakes, she regains consciousness more quickly and clearly because she needed lower doses of propofol and opioid painkillers than patients who heard no music. A new study from Maulana Azad Medical College and Lok Nayak Hospital confirms these effects, offering strong evidence that music can reduce drug requirements and improve surgical recovery.
Music and anaesthesia meet in the operating room
The research, published in the journal Music and Medicine, focused on laparoscopic cholecystectomy, a keyhole procedure to remove the gallbladder. This short surgery demands a swift and alert recovery. “Our aim is early discharge after surgery,” says Dr Farah Husain, senior anaesthetist and certified music therapist. “Patients need to wake clear-headed, alert, and ideally pain-free. Proper pain management also reduces the body’s stress response.” Anaesthesia combines five or six drugs to keep patients asleep, block pain, prevent memory, and relax muscles. Surgeons often add regional nerve blocks to numb the abdominal wall. “General anaesthesia plus blocks is the norm,” says Dr Tanvi Goel, the study’s primary investigator. “We’ve used this method for decades.”
How the body reacts under anaesthesia
Even unconscious, the body reacts to surgery. Heart rates rise, blood pressure spikes, and stress hormones surge. Dr Husain explains that managing this response is crucial to reducing inflammation and speeding recovery. The stress begins before the first incision, with intubation. Anaesthesiologists insert a breathing tube using a laryngoscope, lifting the tongue and soft tissues to guide it into the trachea. “Laryngoscopy and intubation trigger the strongest stress response,” says Dr Sonia Wadhawan, director of anaesthesia at Maulana Azad Medical College. “The patient remembers nothing, but their body reacts with elevated heart rate, blood pressure, and stress hormones.”
Modern anaesthetic drugs and the role of music
Anaesthetic drugs have evolved. Old ether masks have disappeared, replaced by intravenous agents like propofol. “Propofol acts within about 12 seconds,” says Dr Goel. “We prefer it for short surgeries because it avoids the hangover caused by inhaled gases.” The research team wanted to see if music could reduce propofol and fentanyl doses. Lower drug use means faster awakening, steadier vital signs, and fewer side effects. The team conducted a pilot with eight patients, followed by an 11-month trial involving 56 adults aged 20 to 45. All received the same five-drug regimen and wore noise-cancelling headphones. Only one group listened to calming instrumental music, either flute or piano.
Music reduces stress and drug use
“The unconscious mind still remains active,” says Dr Husain. “Even if patients do not remember the music, implicit awareness can create benefits.” Patients exposed to music required less propofol and fentanyl. They showed smoother recoveries, lower cortisol levels, and better blood pressure control during surgery. “Since the ability to hear persists under anaesthesia, music can still shape the brain’s internal state,” the researchers write. Music appears to calm the internal storm. “The auditory pathway remains active even while unconscious,” says Dr Wadhawan. “The brain registers the music, even if patients cannot recall it.”
The unconscious mind and humanising surgery
Scientists have long studied the unconscious mind during surgery. Rare cases of intraoperative awareness show patients remembering fragments of operating-room events. If the brain can register stressful moments during anaesthesia, it can likely register positive experiences, such as music. “We are beginning to explore how the unconscious mind responds to non-drug interventions,” says Dr Husain. “Music offers a way to humanise the operating room.” Music therapy is not new in medicine. Doctors have long used it in psychiatry, stroke recovery, and palliative care. Its entry into anaesthesia marks a subtle shift toward patient wellbeing.
A simple intervention with lasting effects
Even modest reductions in drug use can improve recovery, suggesting hospitals might rethink how they approach surgical care. The research team plans further studies on music-aided sedation, building on these results. One truth emerges from the data: even when the body is still and the mind sleeps, gentle music can help the healing process begin.

