Researchers say they have developed the world’s first accurate blood test to diagnose myalgic encephalomyelitis, or chronic fatigue syndrome (ME/CFS).
Currently, ME/CFS is diagnosed only through symptoms, often leaving patients undiagnosed or misdiagnosed for years.
The new test, developed by scientists at the University of East Anglia and Oxford Biodynamics, detects distinctive DNA-folding patterns in blood.
In trials of 47 ME/CFS patients and 61 healthy adults, the test showed 92% sensitivity and 98% specificity.
Lead researcher Prof Dmitry Pshezhetskiy said the breakthrough could “transform how we diagnose and manage this complex disease.”
Dr Charles Shepherd of the ME Association called the study “an important step forward” but urged further validation.
Other experts, including Prof Chris Ponting, cautioned that claims were “premature” and that more independent studies are essential.
If confirmed, the test could offer earlier diagnosis and treatment for millions living with the often misunderstood condition.
