A new study published in Nature Medicine suggests that following a Mediterranean-style diet may help reduce the risk of dementia, even for people with a strong genetic predisposition. Researchers found that individuals with healthier diets rich in vegetables, fruits, nuts, whole grains, and low in red and processed meats were less likely to develop dementia and showed slower cognitive decline over a 30-year period.
Protective Effect Despite Genetic Risks
One of the strongest genetic risk factors for Alzheimer’s disease is carrying the APOE4 gene variant, which can triple or even increase twelvefold the risk of developing dementia. Yet the study revealed that the benefits of the Mediterranean diet were especially notable among those with two copies of APOE4. Researchers analysed data from over 5,700 participants, combining dietary records, genetic profiles, and long-term cognitive testing. While further research across more diverse populations is needed, the findings highlight that lifestyle choices such as diet can help counter genetic vulnerabilities and may offer a powerful tool in reducing dementia risk.
